The effectiveness of the use of iron caseinate for correcting iron deficiency and hematological parameters under the experimental model of alimentary anemia in rats

Authors

  • Aliaksandr I. Kakhanouski Belarusian State Economic University, 26 Partyzanski Avenue, Minsk 220070, Belarus
  • Nataliya M. Arol Belarusian State University, Niezaliežnasci Avenue, 4, 220030, Minsk, Belarus
  • Katsiaryna Y. Kakhanouskaya Belarusian State Medical University, 83 Dzjarzhinski Avenue, Minsk 220116, Belarus

Keywords:

iron, iron deficiency anemia, iron-protein compounds, casein, caseinate of iron

Abstract

Objective of given research was to study the possibility using of iron caseinate as a feed additive for the prevention of iron deficiency anemia. In experiments on rats, it was established that after the intake of iron caseinate with a mass fraction of elemental iron of 3.65 %, the serum iron level increased significantly within 4 hours. In the model of iron deficiency anemia, after a single intake of iron caseinate at a dose of 2 g/kg, the number of erythrocytes, hemoglobin and hematocrit increased. 

Author Biographies

  • Aliaksandr I. Kakhanouski, Belarusian State Economic University, 26 Partyzanski Avenue, Minsk 220070, Belarus

    lecturer at the faculty of pre-university training

  • Nataliya M. Arol, Belarusian State University, Niezaliežnasci Avenue, 4, 220030, Minsk, Belarus

    PhD (biology), docent; associate professor at the department of biochemistry, faculty of biology

  • Katsiaryna Y. Kakhanouskaya, Belarusian State Medical University, 83 Dzjarzhinski Avenue, Minsk 220116, Belarus

    assistant at the general chemistry department, faculty of pre-university training and vocational guidance

References

  1. Nikoladze M. G., Carput’ I. M. Polysaccharide-protein preparation in the prevention of immune deficiency in piglets with alimentary anemia. Proc. Natl. acad. of sci. of Belarus. Agrar. sci. ser. 2000. No. 4. P. 64 – 69 (in Russ.).
  2. Simonenko S. V., Dimitrieva S. E., Agarkova E. Yu., et al. Investigation of the safety of the protein component of goat’s milk under the influence of ultraviolet radiation. Trudy Belorusskogo gosudarstvennogo universiteta : nauchn. zh. 2009. URL: http://elib. bsu.by/handle/123456789/16276 (date of access: 20.09.2017) (in Russ.).
  3. Osintseva M. A., Braginsky V. I., Osintsev A. M. Investigation of the possibility of magnesium enrichment of milk proteins during their coagulation. Food processing: techniques and technology. 2012. No. 4. Р. 1– 6 (in Russ.).
  4. Kondrakhin I. P. (ed.). Methods of veterinary clinical laboratory diagnostics : handbook. Moscow : KolosS, 2004 (in Russ.).
  5. Krasnikova I. M. Modeling and experimental therapy of iron deficiency anemia in rats. Sib. Med. J. (Irkutsk). 2002. No. 2. Р. 26–27 (in Russ.).
  6. Rebrova O. Yu. Statistical analysis of medical data. Using of the application package Statistica. Moscow : Media Sfera, 2002 (in Russ.).
  7. Maltofer. The drug of the next generation: pharmacokinetics. 2011. URL: https://medi.ru/info/3878 (date of access: 20.09.2017) (in Russ.).

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Published

2018-05-01

Issue

No. 3 (2017): Journal of the Belarusian State University. Biology

Section

Physiology and Сell Biology

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How to Cite

Kakhanouski, A. I., Arol, N. M., & Kakhanouskaya, K. Y. (2018). The effectiveness of the use of iron caseinate for correcting iron deficiency and hematological parameters under the experimental model of alimentary anemia in rats. Experimental Biology and Biotechnology, 3, 10-13. https://journals.bsu.by/index.php/biology/article/view/2455