Quantity estimation of effectiveness of natural polyphenolic compounds as chemical UV-sunscreens

Authors

  • Ahmed Albuhaydar Belarusian State University, Nezavisimosti avenue, 4, 220030, Minsk, Republic of Belarus
  • Alla I. Potapovich Belarusian State University, Nezavisimosti avenue, 4, 220030, Minsk, Republic of Belarus
  • Vladimir A. Kostyuk Belarusian State University, Nezavisimosti avenue, 4, 220030, Minsk, Republic of Belarus

Keywords:

UV-irradiation, photoprotective compounds, chemical UV-sunscreens, plant polyphenols, keratinocytes

Abstract

The aim of research was to quantify in vitro the effectiveness of plant polyphenols as chemical UV-sunscreens. Sun protection factor (SPF) of plant polyphenols (PPs) was determined on the base of spectrophotometric analysis of dilute solutions. Human keratinocytes (HaCaT) viability and proliferation were estimated using PrestoBlue™ reagent. UV-resistant sunscreens possessed very high SPF were found among PPs studied. These compounds effectively protected keratinocytes against UV-induced injury in vitro. We also found that some PPs e. g. resveratrol and chalcone were easily converted by UV-irradiation into extremely cytotoxic intermediates. Our data strongly suggest that PPs may be important component in cosmetic formulations for skin care and sun protection.

Author Biographies

  • Ahmed Albuhaydar, Belarusian State University, Nezavisimosti avenue, 4, 220030, Minsk, Republic of Belarus

    postgraduate student at the department of physiology of human and animals, faculty of biology.

  • Alla I. Potapovich, Belarusian State University, Nezavisimosti avenue, 4, 220030, Minsk, Republic of Belarus

    chief researcher at the science laboratory of physiology at the department of physiology of human and animals, faculty of biology.

  • Vladimir A. Kostyuk, Belarusian State University, Nezavisimosti avenue, 4, 220030, Minsk, Republic of Belarus

    doctor of science (chemistry); head of the laboratory of physiology at the department of physiology of human and animals, faculty of biology.

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Published

2017-12-03

Issue

No. 1 (2017): Journal of the Belarusian State University. Biology

Section

Physiology and Сell Biology

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How to Cite

Albuhaydar, A. ., Potapovich, A. I., & Kostyuk, V. A. (2017). Quantity estimation of effectiveness of natural polyphenolic compounds as chemical UV-sunscreens. Experimental Biology and Biotechnology, 1, 3-12. https://journals.bsu.by/index.php/biology/article/view/2422