Combined algorithm for bone age determination based on hand X-rays analysis

Authors

  • Alexander M. Nedzved Belarusian State University, 4 Niezaliežnasci Avenue, Minsk 220030, Belarus; United Institute of Informatics Problems, National Academy of Sciences of Belarus, 6 Surhanava Street, Minsk 220012, Belarus https://orcid.org/0000-0001-6367-5900
  • Ivan I. Kosik Belarusian State Medical University, 83 Dziaržynskaha Avenue, Minsk 220116, Belarus
  • Ryhor M. Karapetsian Belarusian State Medical University, 83 Dziaržynskaha Avenue, Minsk 220116, Belarus

Keywords:

bone age, X-ray, radiograph, image processing, activation map, convolutional neural network, automation  of diagnostics
Supporting Agencies
This research was partially supported by the project of the Belarusian Republican Foundation for Fundamental Research and Russian Foundation for Basic Research F20R-134 «Development and research of descriptive methods for analyzing dynamic images to automatisation diagnostic procedures» and project of the State Committee on Science and Technology of the Republic of Belarus and Ministry of Science and Technology of the People’s Republic of China F20KITG-006 «Motion analysis of biological objects in video-sequence obtained by high-resolution microscope».

Abstract

In this paper, we investigate the urgent problem associated with bone age determination using hand X-rays. A combined algorithm for the recognition of radiographs is proposed, which uses simultaneous two neural network models, based on Xception and DenseNet169. The method allows to generalize the knowledge of different medical experts and increases the accuracy of bone age prediction in general.

Author Biographies

  • Alexander M. Nedzved, Belarusian State University, 4 Niezaliežnasci Avenue, Minsk 220030, Belarus; United Institute of Informatics Problems, National Academy of Sciences of Belarus, 6 Surhanava Street, Minsk 220012, Belarus

    doctor of science (engineering); dean of the faculty of applied mathematics and computer science, Belarusian State Medical University, and chief researcher at the department of intellectual information systems, United Institute of Informatics Problems, National Academy of Sciences of Belarus

  • Ivan I. Kosik, Belarusian State Medical University, 83 Dziaržynskaha Avenue, Minsk 220116, Belarus

    researcher at the laboratory of information and computer technologies of research division

  • Ryhor M. Karapetsian, Belarusian State Medical University, 83 Dziaržynskaha Avenue, Minsk 220116, Belarus

    head of the laboratory of information and computer technologies of research division

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No. 2 (2020): Journal of the Belarusian State University. Mathematics and Informatics

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Theoretical Foundations of Computer Science

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How to Cite

[1]
Nedzved, A.M. et al. 2020. Combined algorithm for bone age determination based on hand X-rays analysis. Journal of the Belarusian State University. Mathematics and Informatics. 2 (Jul. 2020), 105–114. DOI:https://doi.org/10.33581/2520-6508-2020-2-105-114.