Morphological and spectrometric studies of blood plasma from the patients with cerebral aneurysms

Authors

  • Janne I. Buloichik Belarusian State University, Niezaliežnasci Avenue, 4, 220030, Minsk, Belarus
  • Anatoli P. Zajogin Belarusian State University, Niezaliežnasci Avenue, 4, 220030, Minsk, Belarus
  • Nataliya I. Nechipurenko Republican Research-Practical Center of Neurology and Neurosurgery, 24 F. Skaryny Street, Minsk 220114, Belarus
  • Marya P. Patapovich Belarusian State Academy of Communications, 8/2 F. Skaryny Street, Minsk 220114, Belarus
  • Irina D. Pashkovskaya Republican Research-Practical Center of Neurology and Neurosurgery, 24 F. Skaryny Street, Minsk 220114, Belarus

Keywords:

atomic-emission spectral analysis, blood plasma, biological fluids, drop morphology, laser atomic-emission spectrometry, spatial distribution of calcium, layer-by-layer analysis

Abstract

An integral estimation of the content of essential elements in blood plasma of the patients with cerebral aneurysms is presented. Significant deviations from the normal concentration of the elements under study has been revealed for the majority of the patients both before and after surgery. The obtained results are supported by the morphology of the dried blood-plasma drops and by the quantitative data acquired with the use of laser atomic emission spectrometry for the spatial distribution of calcium on the surface and within the layers of these drops. The exhibited features in the clinical course of the disease point to the necessity to broaden the list of remedies used during medicamentous therapy to correct metabolism of the minerals. The experimental data may form the basis for further improvement of the methods intended to correct insufficient levels of the functional resources of a human organism and for working-out the adequate system of rehabilitation measures.

Author Biographies

  • Janne I. Buloichik, Belarusian State University, Niezaliežnasci Avenue, 4, 220030, Minsk, Belarus

    PhD (chemistry); senior researcher at the department of physical optics and applied informatics, faculty of physics

  • Anatoli P. Zajogin, Belarusian State University, Niezaliežnasci Avenue, 4, 220030, Minsk, Belarus

    doctor of science (physics and mathematics), full professor; professor at the department of laser physics and spectroscopy, faculty of physics

  • Nataliya I. Nechipurenko, Republican Research-Practical Center of Neurology and Neurosurgery, 24 F. Skaryny Street, Minsk 220114, Belarus

    doctor of science (medical sciences), full professor; head of the laboratory of clinical pathophysiology of nervous system

  • Marya P. Patapovich, Belarusian State Academy of Communications, 8/2 F. Skaryny Street, Minsk 220114, Belarus

    PhD (physics and mathematics); associate professor at the department of mathematics and physics, faculty of telecommunication

  • Irina D. Pashkovskaya, Republican Research-Practical Center of Neurology and Neurosurgery, 24 F. Skaryny Street, Minsk 220114, Belarus

    PhD (biology); senior researcher at the laboratory of clinical pathophysiology of nervous system

References

  1. Rumyantseva S. А., Afanasiev V. V., Silina Е. V., et al. [The methods of rational pharmacocorrection and prophylaxis of the secondary ischemia and vasospasm of the patients suffering from disturbances in cerebral circulation of different character]. Tr. patsient. 2010. Vol. 8, No. 6–7. P. 19–25 (in Russ.).
  2. Ugolnick Т. S., Chubukova Т. N. Mechanizms of apoptosis in cerebral ischemia. Probl. health ecol. 2009. No. 3 (21). P. 94–99 (in Russ.).
  3. Novikova L. B., Gromova О. А., Kuramshina D. B. The role of microelements in ischemic stroke. Bashkortostan Med. J. 2010. Vol. 5, No. 4. P. 156–160 (in Russ.).
  4. Kudrin А. V., Gromova О. А. [Microelements in neurology]. Moscow : GEOTAR-Media, 2006 (in Russ.).
  5. Suter P. M. The effects of potassium, magnesium, calcium, and fiber on risk of stroke. Nutr. Rev. 1999. Vol. 57, issue 3. Р. 84–88. DOI: 10.1111/j.1753-4887.1999.tb06928.x.
  6. Gelmers H. J. Effect of calcium antagonists on cerebral circulation. Am. J. Cardiol. 1987. Vol. 59, issue 3. P. B173–B176. DOI: 10.1016/0002-9149(87)90098-1.
  7. Maksimov S. А. Morphology of the solid phase of biological liquids as method of diagnostics in medicine. Bull. Sib. Med. 2007. No. 4. P. 80–85 (in Russ.).
  8. Kraevoy S. А., Koltovoy N. А. [Diagnosis on the basis of one blood drop. Crystallization of biological fluids] : in 4 books. Moscow, 2013. Book 1 : Open drop. P. 67–71 (in Russ.).
  9. Sidorenko Y. S., Shikhlyarova А. I., Segostjantz G. Z. [Regional features in blood morphology of the patients with cancer of lung: the self-organization processes in dynamics of surgery and autohemotransfusion]. Vestnik yuzhnogo nauchn. tsentra. 2005. Vol. 1, No. 4. P. 64–71 (in Russ.).
  10. Buloichik J. I., Veremchuk А. N., Russko Т. А., et al. Morphological and spectrometric studies of the dried blood-drop samples of oncological patients. Vestnik BGU. Ser. 1, Fiz. Mat. Inform. 2015. No. 2. P. 24–30 (in Russ.).
  11. Savkov A. V., Sergei M. A., Buloichik J. I., et al. The use of morphostructural analysis and laser atomic-emission spectrometry of the dried blood plasma drops for diagnosis of prostate carcinioma. Vestnik BGU. Ser. 1, Fiz. Mat. Inform. 2016. No. 3. P. 51–62 (in Russ.).
  12. Buloichik J. I., Maslova G. T., Korzyuk V. V., et al. Using of atomic-emission spectrometry of the dried blood plasma drops in diagnosis and treatment of brain tumors. J. Belarus. State Univ. Phys. 2017. No. 2. P. 17–26 (in Russ.).

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Published

2018-04-29

Issue

No. 1 (2018): Journal of the Belarusian State University. Physics

Section

Optics and Spectroscopy

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How to Cite

(1)
Buloichik, J. I.; Zajogin, A. P.; Nechipurenko, N. I.; Patapovich, M. P.; Pashkovskaya, I. D. Morphological and Spectrometric Studies of Blood Plasma from the Patients With Cerebral Aneurysms. Журнал Белорусского государственного университета. Физика 2018, No. 1, 9-17.