Estimation of the calcium metabolism dynamics for brain ischemic patients using atomic-emission spectrometry of human hair

Authors

  • Mariya P. Patapovich Belarusian State Academy of Communications, 8/2 F. Skaryny Street, Minsk 220114, Belarus
  • Janne I. Buloichik Belarusian State University, 4 Niezaliežnasci Avenue, Minsk 220030, Belarus
  • Irina D. Pashkovskaya Republican Research-Practical Center of Neurology and Neurosurgery, 24 F. Skaryny Street, Minsk 220114, Belarus
  • Nataliya I. Nechipurenko Republican Research-Practical Center of Neurology and Neurosurgery, 24 F. Skaryny Street, Minsk 220114, Belarus
  • Anatoli P. Zajogin Belarusian State University, 4 Niezaliežnasci Avenue, Minsk 220030, Belarus

Keywords:

biological samples, hair, alternating current (a. c.) arc, multichannel atomic-emission spectrometry, retrospective analysis of metabolism, essential elements, aneurysms

Abstract

Analysis of human hair by means of the multichannel atomic-emission spectrometry method has been performed to estimate metabolism of the essential elements in organism of the patients with (cerebrovascular) brain ischemia. Owing to this highly sensitive and fast method, the quantitative variations in the content of these elements may be detected for long periods of time. Quantitative estimates of the elemental content in hair point to the relationship between the course of the disease under study and variations in the content. It has been shown that the critical period in the course of this disease may  be due to the lowered calcium levels. Prompt and effective estimation of the metabolism dynamics is useful for timely prevention of critical conditions. The proposed techniques may be used for early diagnostication and prevention of the brain ischemia.

Author Biographies

  • Mariya P. Patapovich, Belarusian State Academy of Communications, 8/2 F. Skaryny Street, Minsk 220114, Belarus

    PhD (physics and mathematics); associate professor at the department of mathematics and physics; faculty of telecommunication

  • Janne I. Buloichik, Belarusian State University, 4 Niezaliežnasci Avenue, Minsk 220030, Belarus

    PhD (chemistry); senior researcher at the department of physical optics, faculty of physics

  • Irina D. Pashkovskaya, Republican Research-Practical Center of Neurology and Neurosurgery, 24 F. Skaryny Street, Minsk 220114, Belarus

    PhD (biology); senior researcher

  • Nataliya I. Nechipurenko, Republican Research-Practical Center of Neurology and Neurosurgery, 24 F. Skaryny Street, Minsk 220114, Belarus

    doctor of science (medical sciences), full professor; head of the laboratory of clinical pathophysiology of nervous system

  • Anatoli P. Zajogin, Belarusian State University, 4 Niezaliežnasci Avenue, Minsk 220030, Belarus

    doctor of science (physics and mathematics); professor at the department of laser physics and spectroscopy, faculty of physics

References

  1. Rumyantseva S. А., Afanas’ev V. V., Silina E. V., et al. [Methods for the rational pharmacocorrection and prophylaxis of the secondary ischemia and vasospasm of the patients suffering from different circulatory disturbances of the brain]. Trudnyi patsient. 2010. No. 6. P. 19–25 (in Russ.).
  2. Vereshchagin N. V., Gannushkina I. V., Suslina Z. A., et al. [Studies of angioneurology]. Moscow, 2005 (in Russ.).
  3. Skoromets A. A., Skoromets A. P., Skoromets T. A. [Neurological diseases]. Moscow, 2005 (in Russ.).
  4. Fedin A. I., Rumyantseva S. A. [Intensive therapy of ischemic stroke]. Moscow, 2004 (in Russ.).
  5. Yakhno N. N., Stulman D. R. (eds.). [Neural system diseases. Guide book for doctors] : in 2 vol. Moscow, 2003. Vol. 1.
  6. Skvortsova V. I., Krylov V. V. (eds.). [Hemorrhagic stroke] : pract. guide. Moscow, 2005 (in Russ.).
  7. Denisova G. A., Oshchepkova E. V., Balakhonova T. V., et al. [Condition of the blood flow in the pathologically modified main arteries of head of the patients with hypertension]. Terapevticheskii arkhiv. 2000. No. 2. P. 49–52 (in Russ.).
  8. Gusev E. I., Skvortsova V. I. [Brain ischemia]. Moscow, 2001 (in Russ.).
  9. Krylov V. V., Gusev S. A., Gusev A. S. [Vascular spasm on rhexis of the brain aneurysms]. Neirokhirurgiya. 2000. No. 3. P. 4–13 (in Russ.).
  10. Lelyuk V. G., Lelyuk S. E. [Cerebral circulation and arterial pressure]. Moscow, 2004 (in Russ.).
  11. Fedin A. I., Rumyantseva S. A. [Intensive therapy of ischemic stroke]. Moscow, 2004 (in Russ.).
  12. Dorhout Mees S., Rinkel G. J. E., Feigin V. L., et al. Calcium antagonists for aneurysmal subarachnoid haemorrhage. Cochrane Database Syst. Rev. 2007. Vol. 18, issue 3 . CD 000277.
  13. Gelmers H. J. Effect of calcium antagonists on cerebral circulation. Amer. J. Cardiol. 1987. Vol. 59. P. 173–176.
  14. Skalny А. V., Demidov V. А. Hair elemental content as reflection of seasonal changes in provision of child’s organism with major and trace elements. Trace elements med. 2001. Vol. 2, issue 1. P. 36–41 (in Russ.).
  15. Skalny А. V. Reference values of chemical elements concentration in hair, obtained by means of ICP-AES. Trace elements med. 2003. Vol. 4, issue 1. P. 55–56 (in Russ.).
  16. Patapovich М. P., Pashkovskaya I. D., Nechipurenko N. I., et al. Integrated and retrospective estimates of the macro- and microelemental content in hair samples obtained by the multichannel atomic-emission spectrometry method. Vestnik BGU. Ser. 1, Fiz. Mat. Inform. 2015. No. 3. P. 14–20 (in Russ.).
  17. Patapovich M. P., Pashkovskaya I. D., Nechipurenko N. I., et al. Distribution of the essential elements in samples of biological substrates dried on porous surfaces in the presence of precipitates. Vestnik BGU. Ser. 1, Fiz. Mat. Inform. 2016. No. 2. P. 67–72 (in Russ.).
  18. Patapovich M. P., Pashkovskaya I. D., Buloichik J. I., et al. Retrospective estimates of metabolism of the essential elements in a human orqanism by hair with the use of MAES methods. Vestnik BGU. Ser. 1, Fiz. Mat. Inform. 2014. No. 3. P. 16–22 (in Russ.).

Downloads

Published

2017-05-30

Issue

No. 2 (2017): Journal of the Belarusian State University. Physics

Section

Optics and Spectroscopy

License

The authors who are published in this journal agree to the following:

  1. The authors retain copyright on the work and provide the journal with the right of first publication of the work on condition of license Creative Commons Attribution-NonCommercial. 4.0 International (CC BY-NC 4.0).
  2. The authors retain the right to enter into certain contractual agreements relating to the non-exclusive distribution of the published version of the work (e.g. post it on the institutional repository, publication in the book), with the reference to its original publication in this journal.
  3. The authors have the right to post their work on the Internet (e.g. on the institutional store or personal website) prior to and during the review process, conducted by the journal, as this may lead to a productive discussion and a large number of references to this work. (See The Effect of Open Access.)

How to Cite

(1)
Patapovich, M. P.; Buloichik, J. I.; Pashkovskaya, I. D.; Nechipurenko, N. I.; Zajogin, A. P. Estimation of the Calcium Metabolism Dynamics for Brain Ischemic Patients Using Atomic-Emission Spectrometry of Human Hair. Журнал Белорусского государственного университета. Физика 2017, No. 2, 27-33.