Functional properties of immune cells under the influence of extracts of mushrooms Ganoderma lucidum, Lentinula edodes, Boletus edulis

  • Еlena V. Duzh The Institute of Biophysics and Cell Engineering, National Academy of Sciences of Belarus, 27 Akademičnaja Street, Minsk 220072, Belarus https://orcid.org/0000-0002-8172-9092
  • Аndrei Y. Hancharou The Institute of Biophysics and Cell Engineering, National Academy of Sciences of Belarus, 27 Akademičnaja Street, Minsk 220072, Belarus
DOI: https://doi.org/10.33581/2521-1722-2020-3-29-36

Abstract

Тhe water extracts of Basidiomycota division mushrooms such as Boletus edulis, Ganoderma lucidum, Lentinula edodes posessed a wide spectrum of immunomodulatory activity. It was shown that Boletus edulis enhances the expression of surface markers on lymphoid cell lines Jurkat-tat and Daudi, and also increases the expression of reactive oxygen species by dendritic cells, monocytes and peripheral blood neutrophils, activates basophils. There was observed no effect of fungal extracts on NK-cells.

Author Biographies

Еlena V. Duzh, The Institute of Biophysics and Cell Engineering, National Academy of Sciences of Belarus, 27 Akademičnaja Street, Minsk 220072, Belarus

researcher

Аndrei Y. Hancharou, The Institute of Biophysics and Cell Engineering, National Academy of Sciences of Belarus, 27 Akademičnaja Street, Minsk 220072, Belarus

PhD (medicine), docent; director

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Published
2020-12-31
Keywords: Ganoderma lucidum, Lentinula edodes, Boletus edulis, basophils, dendritic cells, cell line, NK-cells, flow cytometry
How to Cite
DuzhЕ. V., & HancharouА. Y. (2020). Functional properties of immune cells under the influence of extracts of mushrooms Ganoderma lucidum, Lentinula edodes, Boletus edulis. Experimental Biology and Biotechnology, 3, 29-36. https://doi.org/10.33581/2521-1722-2020-3-29-36
Issue
No 3 (2020): Journal of the Belarusian State University. Biology
Section
Cell Biology and Physiology

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