Prediction of the course of the breast cancer based on the evaluation of micro-RNA expression

Authors

  • Raisa M. Smoliakova Belarusian State University, International Sakharov Environmental Institute, Dolgobrodskaya street, 23/1, 220070, Minsk, Belarus

Keywords:

anthropogenic load, breast cancer, micro-RNA expression, steroid hormone receptor expression, prognostic factors, risk groups, disease-free survival

Abstract

The molecular genetic profile of the expression of oncogenic miRNA mir-21, mir-373, mir-155, tissue antigens of steroid hormone receptors, epidermal growth factor Her-2 / neu and p53 in breast cancer are analyzed. It was found that the expression level of miR-155, miR-373, miR-21 and the cell regulating cell regulator p53 are independent prognostic risk factors for the relapse of the breast cancer.

Author Biography

  • Raisa M. Smoliakova, Belarusian State University, International Sakharov Environmental Institute, Dolgobrodskaya street, 23/1, 220070, Minsk, Belarus

    doctor of sciences (biology), associate professor; head of the department of general ecology, biology and environmental genetics

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Published

2019-03-03

Issue

No. 3 (2018): Journal of the Belarusian State University. Ecology

Section

Medical Ecology

How to Cite

[1]
Smoliakova, R.M. 2019. Prediction of the course of the breast cancer based on the evaluation of micro-RNA expression. Journal of the Belarusian State University. Ecology. 3 (Mar. 2019), 87–93.