Antioxidant activity of hexahydroquinolines

Authors

  • Ekaterina I. Tarun International Sakharov Environmental Institute, Belarusian State University, 23/1 Daйhabrodskaja Street, Minsk 220070, Belarus
  • Anastasiya V. Dankova International Sakharov Environmental Institute, Belarusian State University, 23/1 Daйhabrodskaja Street, Minsk 220070, Belarus
  • Anatoly N. Pyrko International Sakharov Environmental Institute, Belarusian State University, 23/1 Daйhabrodskaja Street, Minsk 220070, Belarus

Keywords:

antioxidant activity, hexahydroquinolones, fluorescein

Abstract

Comparative characteristics of the antioxidant properties of five different structures held hexahydroquinolones conducted. The dependence of the fluorescence intensity of fluorescein from the logarithm of the concentration of hexahydroquinolones, of which graphically determined indicators IC50. IC50 values in this series was 0,32–5,5∙10-7 М. Hexahydroquinolones have a high antioxidant activity, restoring the fluorescein fluorescence intensity to 76–94 %. An analysis of the contribution of individual functional groups, such as methoxy groups and carboethoxy groups, as well as their amounts and locations relative to each other during the binding of free radicals is done.

Author Biographies

  • Ekaterina I. Tarun, International Sakharov Environmental Institute, Belarusian State University, 23/1 Daйhabrodskaja Street, Minsk 220070, Belarus

    PhD (chemistry), docent; associate professor at the department of environmental chemistry and biochemistry

  • Anastasiya V. Dankova, International Sakharov Environmental Institute, Belarusian State University, 23/1 Daйhabrodskaja Street, Minsk 220070, Belarus

    student

  • Anatoly N. Pyrko , International Sakharov Environmental Institute, Belarusian State University, 23/1 Daйhabrodskaja Street, Minsk 220070, Belarus

    PhD (chemistry), docent; associate professor at the department of environmental chemistry and biochemistry

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Published

2019-11-09

Issue

No. 2 (2019): Journal of the Belarusian State University. Ecology

Section

Medical Ecology

How to Cite

[1]
Tarun, E.I. et al. 2019. Antioxidant activity of hexahydroquinolines. Journal of the Belarusian State University. Ecology. 2 (Nov. 2019), 77–83.