Immunohistochemical characteristics of molecular-biological subtypes of breast cancer

Authors

  • Irina N. Marchuk International Sakharov Environmental Institute, Belarusian State University, 23/1 Daŭhabrodskaja Street, Minsk 220070, Belarus
  • Raisa M. Smolyakova aInternational Sakharov Environmental Institute, Belarusian State University, 23/1 Daŭhabrodskaja Street, Minsk 220070, Belarus
  • Ekaterina M. Shpadaruk International Sakharov Environmental Institute, Belarusian State University, 23/1 Daŭhabrodskaja Street, Minsk 220070, Belarus

Keywords:

immunohistochemical analysis, breast cancer, markers, molecular subtypes

Abstract

Breast cancer is a heterogeneous group of tumors that differ in morphology, clinical course and sensitivity to treatment. There are four molecular subtypes, each of which requires different treatment options, and has a different survival rate. During the immunohistochemical analysis, molecular subtypes of breast cancer were identified according to the levels of expression Her2 / neu, Ki-67, ER, PR, which must be considered to predict the course of the disease and the choice of treatment tactics for patients.

Author Biographies

  • Irina N. Marchuk, International Sakharov Environmental Institute, Belarusian State University, 23/1 Daŭhabrodskaja Street, Minsk 220070, Belarus

    Master's student at the department of general biology and genetics.

  • Raisa M. Smolyakova, aInternational Sakharov Environmental Institute, Belarusian State University, 23/1 Daŭhabrodskaja Street, Minsk 220070, Belarus

    Doctor of sciences (biology), full professor; professor at the department of general biology and genetics.

  • Ekaterina M. Shpadaruk, International Sakharov Environmental Institute, Belarusian State University, 23/1 Daŭhabrodskaja Street, Minsk 220070, Belarus

    PhD (biology); associate professor at the department of general biology and genetics.

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Published

2020-04-13

Issue

No. 3 (2019): Journal of the Belarusian State University. Ecology

Section

Medical Ecology

How to Cite

[1]
Marchuk, I.N. et al. 2020. Immunohistochemical characteristics of molecular-biological subtypes of breast cancer. Journal of the Belarusian State University. Ecology. 3 (Apr. 2020), 58–64.