Structural and functional alterations of platelets in pregnant women with preeclampsia

  • Andrei V. Bakunovich Belarusian State University, International Sakharov Environmental Institute, Dolgobrodskaya street, 23/1, 220070, Minsk, Republic of Belarus
  • Klavdia Ya. Bulanova Belarusian State University, International Sakharov Environmental Institute, Dolgobrodskaya street, 23/1, 220070, Minsk, Republic of Belarus

Abstract

The article presents the characteristics of platelets in normal and pathological conditions of pregnancy. The functional state of platelets, especially regulation of their count, reorganization of plasma membrane and intracellular structures, as well as ability of cells to activate in physiological condition and during preeclampsia, are described. The mechanisms of increased platelet aggregation activity in pregnant women with preeclampsia due to changes in the composition of their plasma membranes, intracellular organelles, changes in the content of cytoplasmic calcium, thromboxane A2 and their correlations with other intracellular messengers are considered.

Author Biographies

Andrei V. Bakunovich, Belarusian State University, International Sakharov Environmental Institute, Dolgobrodskaya street, 23/1, 220070, Minsk, Republic of Belarus

senior lecturer of the department of ecological chemistry and biochemistry

Klavdia Ya. Bulanova, Belarusian State University, International Sakharov Environmental Institute, Dolgobrodskaya street, 23/1, 220070, Minsk, Republic of Belarus

PhD (biological), associate professor; associate professor of the department of ecological chemistry and biochemistry

Published
2019-03-02
Keywords: preeclampsia, platelets, aggregation, thrombin, ADP, thromboxane A2, calcium
How to Cite
Bakunovich, A. V., & Bulanova, K. Y. (2019). Structural and functional alterations of platelets in pregnant women with preeclampsia. Journal of the Belarusian State University. Ecology, 4, 76-83. Retrieved from https://journals.bsu.by/index.php/ecology/article/view/2685
Issue
No 4 (2018): Journal of the Belarusian State University. Ecology
Section
Medical Ecology

Copyright (c) 2018 Journal of the Belarusian State University. Ecology

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.