Inactivating and mutagenic effects of gamma-radiation on the causative agent of (S. typimurium 355) paratyphoid infection in model media

Abstract

It is established, that the ionizing radiation processes evoke strong mutagen action. At radiation basic sensitive structures of a cell-DNA and membranes are damaged. In culture of the irradiated cells biochemical mutants have been found. In normal conditions their growth is not found. Only entering into a nutrient medium of necessary factors of growth (a set of amino acids) has raised their survival rate, but pathogenic properties have disappeared.