Evaluation of cell performance peripheral blood of patients with cancer of the pancreas, received adjuvant radiotherapy and chemoradiotherapy

  • Екатерина Шпадарук International Sakharov Environmental Institute, Belarusian State University
  • Raisa M. Smolyakova International State Environmental Institute, Belarusian State University

Abstract

The article presents an analysis of the data on changes in the indicators of cellular reactivity of homeostasis, as well as parameters of the intoxication indices of the body of patients suffering from pancreatic cancer during combined chemoradiation and radiation treatment. As a result of studies, it was found that in patients with pancreatic cancer during the course of complex chemoradiotherapy, there is a significant change in the content of leukocytes and lymphocytes, as well as the integral indicators of cell homeostasis (index of the ratio of lymphocytes and monocytes). In patients receiving only radiotherapy, a significant change in the relative number of lymphocytes, the index of the ratio of neutrophils and lymphocytes and the index of the ratio of lymphocytes and monocytes was revealed during treatment.

Author Biographies

Екатерина Шпадарук, International Sakharov Environmental Institute, Belarusian State University

PhD (biology); associate professor at the department of general biology and genetics

Raisa M. Smolyakova, International State Environmental Institute, Belarusian State University

doctor of sciences (biology), professor; professor at the department of general biology and genetics

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Published
2020-11-06
Keywords: pancreatic cancer, radiation therapy, radiation exposure, platelets, leukocytes, lymphocytes, neutrophils, monocytes, leukocyte intoxication index according to Y. Y. Kalf-Kalif, leukocyte shift index, neutrophil to lymphocyte ratio index, lymphocyte to monocyte ratio index
How to Cite
Шпадарук, Е., & Smolyakova, R. M. (2020). Evaluation of cell performance peripheral blood of patients with cancer of the pancreas, received adjuvant radiotherapy and chemoradiotherapy. Journal of the Belarusian State University. Ecology, 2, 41-50. Retrieved from https://journals.bsu.by/index.php/ecology/article/view/3067
Issue
No 2 (2020): Journal of the Belarusian State University. Ecology
Section
Radioecology and Radiobiology, Radiation Safety