Using of atomic-emission spectrometry of the dried blood plasma drops in diagnosis and treatment of brain tumors

Authors

  • Janne I. Buloichik Belarusian State University, 4 Niezaliežnasci Avenue, Minsk 220030, Belarus
  • Galina T. Maslova Belarusian State University, 4 Niezaliežnasci Avenue, Minsk 220030, Belarus
  • Victoria V. Korzyuk Belarusian State University, 4 Niezaliežnasci Avenue, Minsk 220030, Belarus
  • Mariya A. Sergei Belarusian State University, 4 Niezaliežnasci Avenue, Minsk 220030, Belarus
  • Anatoli S. Mavrichev N. N. Alexandrov National Cancer Centre of Belarus, 223040, Liasny, Minsk district, Belarus
  • Liliya A. Derzhavets N. N. Alexandrov National Cancer Centre of Belarus, 223040, Liasny, Minsk district, Belarus

Keywords:

biological fluid, drop morphology, laser atomic-emission spectrometry, double laser pulses, spatial distribution, layer-by-layer analysis, calcium

Abstract

With the use of the multichannel atomic-emission spectrometry method, the samples of blood plasma obtained from the patients with brain tumors have been analyzed. The integral estimation of metabolism of the essential elements is given. It has been found that the content of aluminum, iron, calcium, zink was significantly increased for all patients. Semiquantitative results for the calcium distribution over the surface and within the layers of the dried blood-plasma drops have been obtained. It has been revealed that the surface and in depth distribution of calcium in the samples correlates with severity of the disease. Based on analysis of the system albumin – calcium nitrite or – nitrate, the possibility to estimate changes in the transport functions of albumin depending on toxicity of anions has been demonstrated. The proposed method that enables one to estimate the changes in albuminous centers is an effective and sensitive instrument in diagnostication or in treatment of the brain tumors.

Author Biographies

  • Janne I. Buloichik, Belarusian State University, 4 Niezaliežnasci Avenue, Minsk 220030, Belarus

    PhD (chemistry); senior researcher at the department of physical optics, faculty of physics

  • Galina T. Maslova, Belarusian State University, 4 Niezaliežnasci Avenue, Minsk 220030, Belarus

    PhD (biology); associate professor at the department of human and animal physiology, faculty of biology

  • Victoria V. Korzyuk, Belarusian State University, 4 Niezaliežnasci Avenue, Minsk 220030, Belarus

    student at the faculty of biology

  • Mariya A. Sergei, Belarusian State University, 4 Niezaliežnasci Avenue, Minsk 220030, Belarus

    student at the faculty of biology

  • Anatoli S. Mavrichev, N. N. Alexandrov National Cancer Centre of Belarus, 223040, Liasny, Minsk district, Belarus

    doctor of science (medical); deputy director for clinical practice

  • Liliya A. Derzhavets, N. N. Alexandrov National Cancer Centre of Belarus, 223040, Liasny, Minsk district, Belarus

    PhD (biology), head of the clinical diagnostic laboratory

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Published

2017-05-30

Issue

No. 2 (2017): Journal of the Belarusian State University. Physics

Section

Optics and Spectroscopy

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How to Cite

(1)
Buloichik, J. I.; Maslova, G. T.; Korzyuk, V. V.; Sergei, M. A.; Mavrichev, A. S.; Derzhavets, L. A. Using of Atomic-Emission Spectrometry of the Dried Blood Plasma Drops in Diagnosis and Treatment of Brain Tumors. Журнал Белорусского государственного университета. Физика 2017, No. 2, 17-26.