Using of atomic-emission spectrometry of the dried blood plasma drops in diagnosis and treatment of brain tumors

  • Janne I. Buloichik Belarusian State University, 4 Niezaliežnasci Avenue, Minsk 220030, Belarus
  • Galina T. Maslova Belarusian State University, 4 Niezaliežnasci Avenue, Minsk 220030, Belarus
  • Victoria V. Korzyuk Belarusian State University, 4 Niezaliežnasci Avenue, Minsk 220030, Belarus
  • Mariya A. Sergei Belarusian State University, 4 Niezaliežnasci Avenue, Minsk 220030, Belarus
  • Anatoli S. Mavrichev N. N. Alexandrov National Cancer Centre of Belarus, 223040, Liasny, Minsk district, Belarus
  • Liliya A. Derzhavets N. N. Alexandrov National Cancer Centre of Belarus, 223040, Liasny, Minsk district, Belarus

Abstract

With the use of the multichannel atomic-emission spectrometry method, the samples of blood plasma obtained from the patients with brain tumors have been analyzed. The integral estimation of metabolism of the essential elements is given. It has been found that the content of aluminum, iron, calcium, zink was significantly increased for all patients. Semiquantitative results for the calcium distribution over the surface and within the layers of the dried blood-plasma drops have been obtained. It has been revealed that the surface and in depth distribution of calcium in the samples correlates with severity of the disease. Based on analysis of the system albumin – calcium nitrite or – nitrate, the possibility to estimate changes in the transport functions of albumin depending on toxicity of anions has been demonstrated. The proposed method that enables one to estimate the changes in albuminous centers is an effective and sensitive instrument in diagnostication or in treatment of the brain tumors.

Author Biographies

Janne I. Buloichik, Belarusian State University, 4 Niezaliežnasci Avenue, Minsk 220030, Belarus

PhD (chemistry); senior researcher at the department of physical optics, faculty of physics

Galina T. Maslova, Belarusian State University, 4 Niezaliežnasci Avenue, Minsk 220030, Belarus

PhD (biology); associate professor at the department of human and animal physiology, faculty of biology

Victoria V. Korzyuk, Belarusian State University, 4 Niezaliežnasci Avenue, Minsk 220030, Belarus

student at the faculty of biology

Mariya A. Sergei, Belarusian State University, 4 Niezaliežnasci Avenue, Minsk 220030, Belarus

student at the faculty of biology

Anatoli S. Mavrichev, N. N. Alexandrov National Cancer Centre of Belarus, 223040, Liasny, Minsk district, Belarus

doctor of science (medical); deputy director for clinical practice

Liliya A. Derzhavets, N. N. Alexandrov National Cancer Centre of Belarus, 223040, Liasny, Minsk district, Belarus

PhD (biology), head of the clinical diagnostic laboratory

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Published
2017-05-30
Keywords: biological fluid, drop morphology, laser atomic-emission spectrometry, double laser pulses, spatial distribution, layer-by-layer analysis, calcium
How to Cite
Buloichik, J. I., Maslova, G. T., Korzyuk, V. V., Sergei, M. A., Mavrichev, A. S., & Derzhavets, L. A. (2017). Using of atomic-emission spectrometry of the dried blood plasma drops in diagnosis and treatment of brain tumors. Journal of the Belarusian State University. Physics, 2, 17-26. Retrieved from https://journals.bsu.by/index.php/physics/article/view/435
Issue
No 2 (2017): Journal of the Belarusian State University. Physics
Section
Optics and Spectroscopy

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